Chronic limb-threatening ischaemia (CLTI) is a common manifestation of systemic atherosclerosis. It affects 1.3% of American adults at any given time. Inpatient admission related to CLTI are increasing, as are related costs. Contemporary data from Ireland are lacking. This study aims to determine temporal trends in CLTI-related hospital admissions in a single tertiary Irish vascular centre over a 10-year period. The centre serves a large catchment population of approximately 800,000 in the West and North-West of Ireland. The region has high deprivation levels. A retrospective review will be performed of a prospectively maintained patient database. Patient age, gender, smoking history and related co-morbidities (ischaemic heart disease, valvular heart disease, cerebrovascular disease, diabetes, hypertension, chronic obstructive airways disease, renal impairment, cardiac arrhythmias, cardiac failure, cognitive impairment) are recorded. Interventions performed (open surgical revascularisation, endovascular revascularisation, hybrid revascularisation, primary major limb amputation) and 30-day and one-year outcomes (death, ipsilateral limb loss, re-intervention, myocardial infarction, cerebrovascular accident) are recorded. Temporal trends in total comorbidities, interventions and outcomes will be examined to determine whether (i) total CLTI related admission are increasing (ii) total co-morbidities in CLTI patients are increasing, (iii) limb preservation rates are improving and (iv) overall one-year survival is improving.
